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Psychosocial Factors Associated with Sleep Quality and Duration Among Older...

Sleep complaints are common among older adults with chronic pain. Because of the risk of significant side effects, sleep medications are not recommended as first-line treatments. Little is known about...

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Trajectories of Retention in Opioid Agonist Therapy

Long-term engagement in opioid agonist therapy (OAT) has been consistently associated with reduced risk for morbidity and mortality in people with opioid use disorder (OUD). However, the dynamic nature...

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Estimating the impact of wide scale uptake of screening and medications for...

Medications for opioid use disorder (OUD) are the most effective treatment for OUD, but uptake of these life-saving medications has been extremely limited in US prisons and jail settings, and limited...

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Neuroendocrine Effects of Naltrexone Versus Nalmefene

Naltrexone and nalmefene are approved for the treatment of alcohol use disorders, in different countries. Naltrexone is also approved for the treatment for opioid use disorders, most recently in a...

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Phosphates in medications: Impact on Dialysis Patients


Maintaining phosphorus balance in in-center hemodialysis (ICHD) patients is problematic despite recommended dietary restriction, dialysis, and phosphate binder use. Rarely is P content in prescribed...

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Associations between Neighborhood-Level Factors and Opioid-Related Mortality:...

To identify associations between opioid-related mortality and neighborhood-level risk factors.Cross-sectional study.Massachusetts, USA.Using 2011-2014 Massachusetts death certificate data, we...

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A randomised, double-blind, crossover, dose ranging study to determine the...

Pain in people with advanced cancer is prevalent. When a stable dose of opioids is established, people still experience episodic breakthrough pain for which dosing of an immediate release opioid is...

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Safety aspects of opioid-naïve patients with high-grade glioma treated with...

It was suggested that D, L-Methadone might improve the clinical course of glioma patients. Owing to massive press coverage, patients demand the prescription of D, L-Methadone, but regarding its...

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Modeling Combination HCV Treatment and Prevention Strategies in a Network of...

HCV treatment as prevention (TasP) strategies can contribute to HCV micro-elimination, yet complimentary interventions like opioid agonist therapies (OAT) and syringe services programs (SSP) may...

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The impact of an enhanced recovery after minimally invasive surgery program...

To evaluate the effects of an enhanced recovery after minimally invasive surgery (MIS-ERAS) protocol on opioid requirements and post-operative pain in patients undergoing minimally invasive...

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